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Mechanism of Action
In the GI tract, calcium-d-glucarate is metabolized into three compounds, the most active being D-glucaro-1,4-lactone. This metabolite increases the detoxification of carcinogens by inhibiting β-glucuronidase, an enzyme that can deconjugate potential toxins which are being eliminated via the phase II detoxification glucuronida¬tion pathway, allowing them to be reabsorbed back into the body instead of being excreted. With the inhibition of β-glucuronidase, toxins can be safely excreted from the body.
Glucaric acid is not available as a supplement, while calcium-d-glucarate is. Oral supplementation of calcium-d-glucarate is an ideal way to provide the body with an efficient, slow-release source of D-glucaro-1,4-lactone. By supplementing d-glucarates, in this case, the stabilized calcium form, one can favor the body’s natural defense mech¬anism for eliminating toxins, carcinogens and other tumor-promoting drugs, reducing their effects.
Serving Size: 2 capsules
Servings Per Container: 30
Color, size or shape may appear different between lots.